A tool to assess risk of bias in studies estimating the prevalence of mental health disorders (RoB-PrevMH)

Author:

Tonia ThomyORCID,Buitrago-Garcia DianaORCID,Peter NatalieORCID,Mesa-Vieira Cristina,Li Tianjing,Furukawa Toshi A.ORCID,Cipriani AndreaORCID,Leucht StefanORCID,Low NicolaORCID,Salanti GeorgiaORCID

Abstract

AbstractObjectiveBiases affect how certain we are about the available evidence, however no standard tool for assessing the risk of bias (RoB) in prevalence studies exists. For the purposes of a living systematic review on prevalence of mental health disorders during the COVID-19 pandemic, we developed a RoB tool to evaluate prevalence studies in mental health (RoB-PrevMH) and tested interrater reliability.MethodsWe reviewed existing RoB tools for prevalence studies until September 2020, to develop a tool for prevalence studies in mental health. We tested the reliability of assessments by different users of RoB-PrevMH in 83 studies stemming from two systematic reviews of prevalence studies in mental health. We assessed the interrater agreement by calculating the proportion of agreement and Kappa statistic for each item.ResultsRoB-PrevMH consists of three items that address selection bias and information bias. Introductory and signaling questions guide the application of the tool to the review question. The interrater agreement for the three items was 83%, 90% and 93%. The weighted kappa was 0.63 (95% CI 0.54 to 0.73), 0.71 (95% CI 0.67 to 0.85) and 0.32 (95% CI –0.04 to –0.63), respectively.ConclusionsWe developed a brief, user friendly, and adaptable tool for assessing RoB in studies on prevalence of mental health disorders. Initial results for interrater agreement were fair to substantial. The tool’s validity, reliability, and applicability should be assessed in future projects.

Publisher

Cold Spring Harbor Laboratory

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