APRI score is not predictive of post-surgical outcomes in cholangiocarcinoma patients

Abstract

AbstractObjectiveTo assess the utility of aminotransferase-platelet ratio index (APRI) score in prognosticating post-surgical outcomes in cholangiocarcinoma patients.Methods152 cholangiocarcinoma patients at the Mayo Clinic that underwent surgical resection were retrospectively analyzed. Statistical analyses were done to determine the relationship between APRI score and demographic factors, laboratory values, pathological features, and outcomes data.ResultsNo relationship between APRI score and demographic factors was identified. There was a correlation between APRI score and ALT, albumin, and bilirubin, but the remaining laboratory parameters showed no correlation. APRI score did not prove to be useful as a prognostic tool as it did not correlate with tumor pathology features and did not correlate with post-surgical recurrence and mortality.ConclusionWe found that APRI score was not a prognostic tool for post-surgical outcomes in cholangiocarcinoma patients.