Influence of Hydrolysis Susceptibility and Hydrophobicity of SN-38 Nano-Prodrugs on Their Anticancer Activity

Author:

Koseki Yoshitaka1,Ikuta Yoshikazu1,Cong Liman2,Takano-Kasuya Mayumi2,Tada Hiroshi3,Watanabe Mika4,Gonda Kohsuke2,Ishida Takanori3,Ohuchi Noriaki3,Tanita Keita1,Taemaitree Farsai1,Dao Anh Thi Ngoc1,Onodera Tsunenobu1,Oikawa Hidetoshi1,Kasai Hitoshi1

Affiliation:

1. Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, Japan

2. Department of Medical Physics, Graduate School of Medicine, Tohoku University, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan

3. Department of Breast and Endocrine Surgical Oncology, Graduate School of Medicine, Tohoku University, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan

4. Department of Pathology, Tohoku University Hospital, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan

Publisher

The Chemical Society of Japan

Subject

General Chemistry

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