DNA Cleavage through Reductive Dioxygen Activation by Iron-Bleomycin Mimics with Carboxamido Ligation: Correlation between DNA Cleavage Efficacy and Redox Potential

Author:

Nomura Akiko1,Iwamoto Yuji12,Arakawa Kengo2,Kashida Akihiro2,Kodera Masahito12,Hitomi Yutaka12

Affiliation:

1. Center for Nanoscience Research, Doshisha University, 1-3 Tatara Miyakodani, Kyotanabe, Kyoto 610-0321

2. Department of Applied Chemistry, Graduate School of Science and Engineering, Doshisha University, 1-3 Tatara Miyakodani, Kyotanabe, Kyoto 610-0321

Publisher

The Chemical Society of Japan

Subject

General Chemistry

Reference22 articles.

1. B. A. Chabner, D. L. Longo, Cancer Chemotherapy and Biotherapy, Lippincott Williams & Wilkins, Philadelphia, 2010, p. 848.

2. Mechanisms of bleomycin-induced DNA degradation

3. Curing metastatic testicular cancer

4. Bleomycin-Induced Pneumonitis

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