Synthesis of Novel Orally Active Prodrugs by Introduction of an Acyloxymethyl Carbamate Moiety into Cefetamet Pivoxil
Author:
Affiliation:
1. Shionogi Pharmaceutical Research Center, Shionogi & Co., Ltd, 1-1 Futabacho 3-chome, Toyonaka, Osaka 561-0825, Japan
Publisher
The Chemical Society of Japan
Subject
General Chemistry
Link
http://www.journal.csj.jp/doi/pdf/10.1246/cl.200599
Reference19 articles.
1. Switch over from intravenous to oral therapy: A concise overview
2. Switch therapy: the theory and practice of early change from parenteral to non-parenteral antibiotic administration
3. Cost minimization analysis on IV to oral conversion of antimicrobial agent by the clinical pharmacist intervention
4. Pharmacokinetics of cefetamet (Ro 15-8074) and cefetamet pivoxil (Ro 15-8075) after intravenous and oral doses in humans
5. Synthesis and oral activity of ME 1207, a new orally active cephalosporin.
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