The Importance Of Human Induced Pluripotent Stem Cells In Neurodegenerative Disorders

Abstract

Previous studies which helped researchers to understand embryonic development revealed multiple aspects of differentiated of human somatic cells into various types of cells. Human induced pluripotent stem cells (iPSCs) are somatic cells that are reprogrammed using certain factors that possesses pluripotent property that leads to self-proliferation and/or differentiation into various other cell types. The recent advancements using induced pluripotent stem cells have opened multiple avenues of research related to therapies. This has led to an enormous interest among scientists regarding its application ranging from regenerative medicine to modeling diseases. For example, Parkinson’s disease, Alzheimer’s disease among others could be treated with iPSC therapy or replacement tissues. In this review, we discuss the importance of iPSCs in the clinical perspective of treatment and management of disease.