SYNTHESIS OF SOME DIAZINE AND TRIAAZOLE DERIVATIVES FROM FURFURAL

Abstract

The synthesis of heterocyclic compounds especially when their structure containing nitrogen ,oxygen and sulfur atoms  are growing up  due to their wide spread  in nature ,many mechanistic pathways to reach the target with nearly  negligible loss of their dose and there are numerous  me thods to derivatives their structures  There for the development in hetero cyclic synthesis will provide new metabolic pathways when these compounds  have succeeded to be used as drug ,Moreover it was known for  long time that about 95 % of cancer drugs  are heterocyclic compounds .There are also many methods found in the literature for the synthesis of both triazoles and trdiazines from different routes In this investigation furfural was used as precursor for the synthesis of some new diazine and triazole derivatives (3-11).The synthesized compounds were characterized by IR ,and    1HNMR and are  discussed.