Cancer in Kidney Transplant Recipients: Latest Findings

Abstract

Acute renal failure in cancer patients may be due to the existence of tumor cell lysis, in which large amounts of potassium, phosphate, and nucleic acids are released into the bloodstream and cause a cancerous emergency [1]. In addition, it causes metabolic abnormalities that lead to the formation of calcium phosphate, which precipitates into the tissues and some into the kidneys. Metabolic abnormalities increase levels of uric acid, which precipitates in the kidneys. Both situations can lead to End-Stage Renal Failure (ESRF) [2]. The medical solution at this stage is for patients on dialysis or solid organ kidney transplantation.