Personalized correction of lipid metabolism in blood of inhabitants of the metropolis under high technogenic load

Abstract

Introduction: The purpose of the study was to evaluate the effectiveness of personalized correction of violations of fat metabolism when using an individually prescribed vitamin and mineral complex. Methods: The study included 313 volunteers who belong to the category of "practically healthy people" and do not have a severe chronic pathology. All participants in the study were randomly assigned to the main group (n = 197) and the comparison group (n = 116). At the first stage, the state of blood lipid metabolism was evaluated in the representatives of both formed groups, and the laboratory examination complex included: determination of the total cholesterol concentration, the concentration of low- and high-density cholesterol, and the level of triglycerides. Patients of the main group were additionally monitored for the level of blood trace elements and a wide range of biochemical parameters. Taking into account the results of the latter, the composition of the vitamin and mineral complex was individually selected for them. The duration of its daily intake for all members of the main group was 60 days. Patients in the comparison group received a placebo for a similar time period. Result & Conclusion: The study of the effectiveness of the personalized vitamin and mineral complex allowed us to demonstrate the positive effect of daily intake (for 2 months) on the parameters of blood lipid metabolism. It was manifested in a decrease in the total concentration of cholesterol, which was mainly provided by a decrease in the level of cholesterol contained in low-density.