DNA Methylation in Cancer: A Gene Silencing Mechanism and the Clinical Potential of Its Biomarkers
Author:
Affiliation:
1. Department of Molecular Pathology, Tohoku University Graduate School of Medicine
2. Center for Regulatory Epigenome and Diseases, Tohoku University Graduate School of Medicine
Publisher
Tohoku University Medical Press
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
https://www.jstage.jst.go.jp/article/tjem/229/3/229_173/_pdf
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3. Baylin, S.B. & Jones, P.A. (2011) A decade of exploring the cancer epigenome-Biological and translational implications. Nat. Rev. Cancer, 11, 726-734.
4. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
5. The Protein CTCF Is Required for the Enhancer Blocking Activity of Vertebrate Insulators
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