Severe Acute Otitis Media Caused by Mucoid Streptococcus Pyogenes in a Previously Healthy Adult

Author:

Kakuta Risako12,Yano Hisakazu2,Hidaka Hiroshi1,Miyazaki Hiromitsu1,Irimada Mihoko3,Oda Kiyoshi3,Arai Kazuaki4,Ozawa Daiki12,Takahashi Takashi45,Kaku Mitsuo2,Katori Yukio1

Affiliation:

1. Department of Otolaryngology, Head and Neck Surgery, Tohoku University Graduate School of Medicine

2. Department of Infection Control and Laboratory Diagnostics, Tohoku University Graduate School of Medicine

3. Department of Otolaryngology, Tohoku Rosai Hospital

4. Laboratory of Infectious Diseases, Kitasato Institute for Life Sciences, Kitasato University

5. Laboratory of Infectious Diseases, Graduate School of Infection Control Sciences, Kitasato University

Publisher

Tohoku University Medical Press

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference21 articles.

1. Alós, J.I., Aracil, B., Oteo, J. & Gómez-Garcés, J.L. (2003) Significant increase in the prevalence of erythromycin-resistant, clindamycin- and miocamycin-susceptible (M phenotype) Streptococcus pyogenes in Spain. J. Antimicrob. Chemother., 51, 333-337.

2. Arai, K., Hirakata, Y., Yano, H., Kanamori, H., Endo, S., Hirotani, A., Abe, Y., Nagasawa, M., Kitagawa, M., Aoyagi, T., Hatta, M., Yamada, M., Nishimaki, K., Takayama, Y., Yamamoto, N., et al. (2011) Emergence of fluoroquinolone-resistant Streptococcus pyogenes in Japan by a point mutation leading to a new amino acid substitution. J. Antimicrob. Chemother., 66, 494-498.

3. Ardanuy, C., Domenech, A., Rolo, D., Calatayud, L., Tubau, F., Ayats, J., Martín, R. & Liñares, J. (2010) Molecular characterization of macrolide- and multidrug-resistant Streptococcus pyogenes isolated from adult patients in Barcelona, Spain (1993-2008). J. Antimicrob. Chemother., 65, 634-643.

4. Baker, G.C., Smith, J.J. & Cowan, D.A. (2003) Review and re-analysis of domain-specific 16S primers. J. Microbiol. Methods, 55, 541-555.

5. Beall, B., Facklam, R. & Thompson, T. (1996) Sequencing emm-specific PCR products for routine and accurate typing of group A streptococci. J. Clin. Microbiol., 34, 953-958.

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