New-Onset or Exacerbation of Diabetes Mellitus Is a Clue to the Early Diagnosis of Pancreatic Cancer

Author:

Takikawa Tetsuya1,Kikuta Kazuhiro1,Kume Kiyoshi1,Hamada Shin1,Miura Shin1,Yoshida Naoki1,Hongo Seiji1,Tanaka Yu1,Matsumoto Ryotaro1,Sano Takanori1,Ikeda Mio1,Iseki Masahiro2,Unno Michiaki2,Masamune Atsushi1

Affiliation:

1. Division of Gastroenterology, Tohoku University Graduate School of Medicine

2. Department of Surgery, Tohoku University Graduate School of Medicine

Publisher

Tohoku University Medical Press

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference35 articles.

1. Aggarwal, G., Ramachandran, V., Javeed, N., Arumugam, T., Dutta, S., Klee, G.G., Klee, E.W., Smyrk, T.C., Bamlet, W., Han, J.J., Vittar, N.B.R., De Andrade, M., Mukhopadhyay, D., Petersen, G.M., Fernandez-Zapico, M.E., et al. (2012) Adrenomedullin is up-regulated in patients with pancreatic cancer and causes insulin resistance in β cells and mice. Gastroenterology, 143, 1510-1517. e1.

2. American Diabetes Association (2018) 2. Classification and diagnosis of diabetes: standards of medical care in diabetes-2018. Diabetes Care, 41, S13-S27.

3. Amin, M.B., Edge, S., Greene, F., Byrd, D.R., Brookland, R.K., Washington, M.K., Gershenwald, J.E., Compton, C.C., Hess, K.R., Sullivan, D.C., Jessup, J.M., Brierley, J.D., Gaspar, L.E., Schilsky, R.L., Balch, C.M. et al. (2017) AJCC Cancer Staging Manual, 8th ed., Springer International Publishing, NY, USA.

4. Aslanian, H.R., Lee, J.H. & Canto, M.I. (2020) AGA clinical practice update on pancreas cancer screening in high-risk individuals: expert review. Gastroenterology, 159, 358-362.

5. Batabyal, P., Vander Hoorn, S., Christophi, C. & Nikfarjam, M. (2014) Association of diabetes mellitus and pancreatic adenocarcinoma: a meta-analysis of 88 studies. Ann. Surg. Oncol., 21, 2453-2462.

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