Troglitazone Ameliorates Abnormal Activity of Protein Tyrosine Phosphatase in Adipose Tissues of Otsuka Long-Evans Tokushima Fatty Rats.
Author:
Affiliation:
1. The First Department of Medicine, Hokkaido University School of Medicine
2. Department of Clinical Physiology, Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido
Publisher
Tohoku University Medical Press
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.jstage.jst.go.jp/article/tjem/197/3/197_3_169/_pdf
Reference43 articles.
1. Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver
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3. Increased abundance of the receptor-type protein-tyrosine phosphatase LAR accounts for the elevated insulin receptor dephosphorylating activity in adipose tissue of obese human subjects.
4. Alterations in skeletal muscle protein-tyrosine phosphatase activity and expression in insulin-resistant human obesity and diabetes.
5. Improved sensitivity to insulin in obese subjects following weight loss is accompanied by reduced protein-tyrosine phosphatases in adipose tissue
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