Detection of Pivaloylcarnitine in Pediatric Patients with Hypocarnitinemia after Long-Term Administration of Pivalate-Containing Antibiotics-Reference-Cited by-同舟云学术

Detection of Pivaloylcarnitine in Pediatric Patients with Hypocarnitinemia after Long-Term Administration of Pivalate-Containing Antibiotics

Published:2010 Issue:4 Volume:221 Page:309-313
ISSN:0040-8727
Container-title:The Tohoku Journal of Experimental Medicine
language:en
Short-container-title:Tohoku J. Exp. Med.

Author:

Nakajima Yoko¹,Ito Tetsuya¹,Maeda Yasuhiro²,Ichiki Sayaka¹,Sugiyama Naruji³,Mizuno Mihoko⁴,Makino Yasuko⁵,Sugiura Tokio⁵,Kurono Yukihisa²,Togari Hajime¹

Affiliation:

1. Department of Pediatrics and Neonatology, Nagoya City University, Graduate School of Medical Sciences

2. Laboratory of Hospital Pharmacy, Nagoya City University, Graduate School of Pharmaceutical Science

3. Department of Pediatrics, Aichi-Gakuin University, School of Pharmacology

4. Department of Pediatrics, Daido Hospital

5. Department of Pediatrics, Toyohashi Municipal Hospital

Publisher

Tohoku University Medical Press

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.jstage.jst.go.jp/article/tjem/221/4/221_4_309/_pdf

Reference8 articles.

1. Brass, E.P. (2002) Pivalate-generating prodrugs and carnitine homeostasis in man. Pharmacol. Rev., 54, 589-598.

2. Impact on carnitine homeostasis of short-term treatment with the pivalate prodrug cefditoren pivoxil

3. Cavedon, C.T., Bourdoux, P., Mertens, K., Van Thi, H.V., Herremans, N., de Laet, C. & Goyens, P. (2005) Age-related variations in acylcarnitine and free carnitine concentrations measured by tandem mass spectrometry. Clin. Chem., 51, 745-752.

4. Holme, E., Jodal, U., Linstedt, S. & Nordin, I. (1992) Effects of pivalic acid-containing prodrugs on carnitine homeostasis and on response to fasting in children. Scand. J. Clin. Lab. Invest., 52, 361-372.

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