Bromocriptine, a Dopamine Agonist, Increases Growth Hormone Secretion in a Patient with Acromegaly

Author:

Arihara Zenei1,Sakurai Kanako1,Yamashita Rika1,Niitsuma Satsuki1,Ueno Takayuki1,Yamamura Nao12,Yamada Shozo3,Inoshita Naoko4,Takahashi Kazuhiro2

Affiliation:

1. Department of Endocrinology and Metabolism, Sendai Medical Center

2. Department of Endocrinology and Applied Medical Science, Tohoku University Graduate School of Medicine

3. Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital

4. Department of Pathology, Toranomon Hospital

Publisher

Tohoku University Medical Press

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference26 articles.

1. Abe, H., Molitch, M.E., Van Wyk, J.J. & Underwood, L.E. (1983) Human growth hormone and somatomedin C suppress the spontaneous release of growth hormone in unanesthetized rats. Endocrinology, 113, 1319-1324.

2. Arce, V., Lima, L., Lois, N., Rodríguez, A., Díaz, M.J., Tresguerres, J.A. & Devesa, J. (1991) Role of central dopaminergic pathways in the neural control of growth hormone secretion in normal men: studies with metoclopramide. Neuroendocrinology, 53, 143-149.

3. Avram, A.M., Jaffe, C.A., Symons, K.V. & Barkan, A.L. (2005) Endogenous circulating ghrelin does not mediate growth hormone rhythmicity or response to fasting. J. Clin. Endocrinol. Metab., 90, 2982-2987.

4. Ballaré, E., Mantovani, S., Bassetti, M., Lania, A. & Spada, A. (1997) Immunodetection of G proteins in human pituitary adenomas: evidence for a low expression of proteins of the Gi subfamily. Eur. J. Endocrinol., 137, 482-489.

5. Bush, Z.M. & Vance, M.L. (2008) Management of acromegaly: is there a role for primary medical therapy? Rev. Endocr. Metab. Disord., 9, 83-94.

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