N-Linked Glycosylation at an Appropriate Position in the Pre-S2 Domain Is Critical for Cellular and Humoral Immunity against Middle HBV Surface Antigen-Reference-Cited by-同舟云学术

N-Linked Glycosylation at an Appropriate Position in the Pre-S2 Domain Is Critical for Cellular and Humoral Immunity against Middle HBV Surface Antigen

Published:2015 Issue:2 Volume:236 Page:131-138
ISSN:0040-8727
Container-title:The Tohoku Journal of Experimental Medicine
language:en
Short-container-title:Tohoku J. Exp. Med.

Author:

Liu Hao¹²,Wang Shixia³⁴,Jia Yiqiong²,Li Jun²,Huang Zuhu⁴²,Lu Shan³⁴,Xing Yiping²

Affiliation:

1. Department of Infectious Diseases, Nanjing Children's Hospital, Affiliated to Nanjing Medical University

2. Department of Infectious Diseases, The First Affiliated Hospital of Nanjing Medical University

3. Department of Medicine, University of Massachusetts Medical School

4. China-US Vaccine Research Center, Nanjing Medical University

Publisher

Tohoku University Medical Press

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

https://www.jstage.jst.go.jp/article/tjem/236/2/236_131/_pdf

Reference31 articles.

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2. Chen, H., Wen, B., Deng, Y., Wang, W., Yin, X., Guan, J., Ruan, L. & Tan, W. (2011) Enhanced effect of DNA immunization plus in vivo electroporation with a combination of hepatitis B virus core-PreS1 and S-PreS1 plasmids. Clin. Vaccine Immunol., 18, 1789-1795.

3. Cheng, K.C. & Moss, B. (1987) Selective synthesis and secretion of particles composed of the hepatitis B virus middle surface protein directed by a recombinant vaccinia virus: induction of antibodies to pre-S and S epitopes. J. Virol., 61, 1286-1290.

4. Chuai, X., Chen, H., Wang, W., Deng, Y., Wen, B., Ruan, L. & Tan, W. (2013) Poly(I:C)/alum mixed adjuvant priming enhances HBV subunit vaccine-induced immunity in mice when combined with recombinant adenoviral-based HBV vaccine boosting. PloS One, 8, e54126.

5. Cova, L. (2012) Progress in DNA vaccination against HBV infection. Future Virol., 7, 149-160.

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