Minocycline and Pyrrolidine Dithiocarbamate Attenuate Hypertension via Suppressing Activation of Microglia in the Hypothalamic Paraventricular Nucleus-Reference-Cited by-同舟云学术

Minocycline and Pyrrolidine Dithiocarbamate Attenuate Hypertension via Suppressing Activation of Microglia in the Hypothalamic Paraventricular Nucleus

Published:2023 Issue:2 Volume:259 Page:163-172
ISSN:0040-8727
Container-title:The Tohoku Journal of Experimental Medicine
language:en
Short-container-title:Tohoku J. Exp. Med.

Author:

Liu Xiao-Jing¹,Yu Xiao-Jing²,Su Yu-Kun³,Qiao Jin-An⁴,Sun Yao-Jun⁵,Bai Xiao-Jie⁵,Zhang Nana⁶,Yang Hui-Yu⁷,Yin Li-Xi⁸,Kang Yu-Ming²,Yang Zhi-Ming⁷

Affiliation:

1. The Second Clinical Medical College, Shanxi Medical University

2. Department of Physiology and Pathophysiology, Xi’an Jiaotong University School of Basic Medical Sciences, Shaanxi Engineering and Research Center of Vaccine, Key Laboratory of Environment and Genes Related to Diseases of Education Ministry of China

3. Hemodialysis Center, Shanxi Second People’s Hospital

4. Institute of Pediatric Diseases, Xi’an Children’s Hospital

5. Key Laboratory of Cellular Physiology at Shanxi Medical University, Ministry of Education, and the Department of Physiology, Shanxi Medical University

6. Department of Hypertension, The First Hospital of Shanxi Medical University

7. Department of Cardiology, The Second Hospital of Shanxi Medical University

8. Basic Medical College of Shanxi Medical University

Publisher

Tohoku University Medical Press

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

https://www.jstage.jst.go.jp/article/tjem/259/2/259_2022.J102/_pdf

Reference31 articles.

1. Agarwal, D., Welsch, M.A., Keller, J.N. & Francis, J. (2011) Chronic exercise modulates RAS components and improves balance between pro- and anti-inflammatory cytokines in the brain of SHR. Basic Res. Cardiol., 106, 1069-1085.

2. Biancardi, V.C., Stranahan, A.M., Krause, E.G., de Kloet, A.D. & Stern, J.E. (2016) Cross talk between AT1 receptors and Toll-like receptor 4 in microglia contributes to angiotensin II-derived ROS production in the hypothalamic paraventricular nucleus. Am. J. Physiol. Heart Circ. Physiol., 310, H404-415.

3. Cai, W., Lang, M., Jiang, X., Yu, Q., Zhou, C., Zou, W., Zhang, X. & Lei, J. (2020) Correlation among high salt intake, blood pressure variability, and target organ damage in patients with essential hypertension: study protocol clinical trial (SPIRIT compliant). Medicine (Baltimore), 99, e19548.

4. Campos, R.R., Oliveira-Sales, E.B., Nishi, E.E., Paton, J.F. & Bergamaschi, C.T. (2015) Mechanisms of renal sympathetic activation in renovascular hypertension. Exp. Physiol., 100, 496-501.

5. Chen, D., Zang, Y.H., Qiu, Y., Zhang, F., Chen, A.D., Wang, J.J., Chen, Q., Li, Y.H., Kang, Y.M. & Zhu, G.Q. (2019) BCL6 attenuates proliferation and oxidative stress of vascular smooth muscle cells in hypertension. Oxid. Med. Cell. Longev., 2019, 5018410.