Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study

Author:

Chen Po-Sheng1,Lin Jia-Ling1,Lin Hui-Wen12,Lin Sheng-Hsiang234,Li Yi-Heng1

Affiliation:

1. Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University

2. Biostatistics Consulting Center, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University

3. Institute of Clinical Medicine, College of Medicine, National Cheng Kung University

4. Department of Public Health, College of Medicine, National Cheng Kung University

Publisher

Tohoku University Medical Press

Reference39 articles.

1. Amarenco, P., Bogousslavsky, J., Callahan, A. 3rd, Goldstein, L.B., Hennerici, M., Rudolph, A.E., Sillesen, H., Simunovic, L., Szarek, M., Welch, K.M. &Zivin, J.A.;Stroke Prevention by Aggressive Reduction in Cholesterol Levels Investigators (2006) High-dose atorvastatin after stroke or transient ischemic attack. N. Engl. J. Med., 355, 549-559.

2. Catapano, A.L. (2010) Pitavastatin - pharmacological profile from early phase studies. Atheroscler. Suppl., 11, 3-7.

3. Chen, P.S., Lee, M., Tang, S.C., Huang, P.H., Yeh, H.I., Jia-Yin Hou, C., Hsieh, I.C., Lee, J.T., Jeng, J.S. & Li, Y.H. (2022) 2022 focused update of the 2017 Taiwan lipid guidelines for high risk patients: coronary artery disease, peripheral artery disease and ischemic stroke. J. Formos. Med. Assoc., 121, 1363-1370.

4. Cheng, C.L., Lee, C.H., Chen, P.S., Li, Y.H., Lin, S.J. & Yang, Y.H. (2014) Validation of acute myocardial infarction cases in the national health insurance research database in taiwan. J. Epidemiol., 24, 500-507.

5. Cheng, Y., Qiao, L., Jiang, Z., Dong, X., Feng, H., Gui, Q., Lu, Y. & Liang, Y. (2020) Significant reduction in the LDL cholesterol increases the risk of intracerebral hemorrhage: a systematic review and meta-analysis of 33 randomized controlled trials. Am. J. Transl. Res., 12, 463-477.

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