Switching to Tenofovir Alafenamide Fumarate in Chronic Hepatitis B Patients Who Had Detectable HBV DNA during Treatment with Entecavir

Author:

Sato Kosuke1,Inoue Jun1,Akahane Takehiro2,Kobayashi Tomoo3,Takai Satoshi4,Nakamura Takuya5,Sato Toshihiro6,Kimura Osamu7,Ninomiya Masashi1,Iwata Tomoaki1,Sano Akitoshi1,Tsuruoka Mio1,Onuki Masazumi1,Sawahashi Satoko1,Niitsuma Hirofumi1,Masamune Atsushi1

Affiliation:

1. Division of Gastroenterology, Tohoku University Graduate School of Medicine

2. Department of Gastroenterology, Japanese Red Cross Ishinomaki Hospital

3. Department of Hepatology, Tohoku Rosai Hospital

4. Department of Gastroenterology, Iwaki City Medical Center

5. Department of Gastroenterology, Yamagata City Hospital Saiseikan

6. LC Clinic Sendai

7. Department of Gastroenterology, South Miyagi Medical Center

Publisher

Tohoku University Medical Press

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference29 articles.

1. Agarwal, K., Brunetto, M., Seto, W.K., Lim, Y.S., Fung, S., Marcellin, P., Ahn, S.H., Izumi, N., Chuang, W.L., Bae, H., Sharma, M., Janssen, H.L.A., Pan, C.Q., Çelen, M.K., Furusyo, N., et al. (2018) 96 weeks treatment of tenofovir alafenamide vs. tenofovir disoproxil fumarate for hepatitis B virus infection. J. Hepatol., 68, 672-681.

2. Buti, M., Gane, E., Seto, W.K., Chan, H.L., Chuang, W.L., Stepanova, T., Hui, A.J., Lim, Y.S., Mehta, R., Janssen, H.L., Acharya, S.K., Flaherty, J.F., Massetto, B., Cathcart, A.L., Kim, K., et al. (2016) Tenofovir alafenamide versus tenofovir disoproxil fumarate for the treatment of patients with HBeAg-negative chronic hepatitis B virus infection: a randomised, double-blind, phase 3, non-inferiority trial. Lancet Gastroenterol. Hepatol., 1, 196-206.

3. Chan, H.L., Fung, S., Seto, W.K., Chuang, W.L., Chen, C.Y., Kim, H.J., Hui, A.J., Janssen, H.L., Chowdhury, A., Tsang, T.Y., Mehta, R., Gane, E., Flaherty, J.F., Massetto, B., Gaggar, A., et al. (2016) Tenofovir alafenamide versus tenofovir disoproxil fumarate for the treatment of HBeAg-positive chronic hepatitis B virus infection: a randomised, double-blind, phase 3, non-inferiority trial. Lancet Gastroenterol. Hepatol., 1, 185-195.

4. European Association for the Study of the Liver (2017) EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection. J. Hepatol., 67, 370-398.

5. Inoue, J., Akahane, T., Kobayashi, T., Obara, N., Umetsu, T., Kakazu, E., Ninomiya, M., Iwata, T., Sano, A., Tsuruoka, M., Sato, K. & Masamune, A. (2021) Switching to tenofovir disoproxil fumarate in entecavir-treated chronic hepatitis B patients: a pilot randomized controlled study. Biomed. Rep., 14, 20.

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