Disruption of Plasminogen Activator Inhibitor-1 Gene Enhances Spontaneous Enlargement of Mouse Airspace with Increasing Age-Reference-Cited by-同舟云学术

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Disruption of Plasminogen Activator Inhibitor-1 Gene Enhances Spontaneous Enlargement of Mouse Airspace with Increasing Age

Published:2010 Issue:4 Volume:222 Page:291-296
ISSN:0040-8727
Container-title:The Tohoku Journal of Experimental Medicine
language:en
Short-container-title:Tohoku J. Exp. Med.

Author:

Hu Hua¹²,Zhao Yanyan³,Xiao Yao²,Zhang Ruxin¹,Song Houyan²

Affiliation:

1. Department of ENT, Huadong Hospital, Shanghai Medical School, Fudan University

2. Department of Molecular Genetics and the Key Laboratory of Molecular Medicine, Ministry of Education, Shanghai Medical School, Fudan University

3. Department of neurology, Xinhua Hospital (Chong Ming), Shanghai Jiaotong University

Publisher

Tohoku University Medical Press

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.jstage.jst.go.jp/article/tjem/222/4/222_4_291/_pdf

Reference25 articles.

1. Bonniaud, P., Kolb, M., Galt, T., Robertson, J., Robbins, C., Stampfli, M., Lavery, C., Margetts, P.J., Roberts, A.B. & Gauldie, J. (2004) Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis. J. Immunol., 173, 2099-2108.

2. Cho, S.H., Ryu, C.H. & Oh, C.K. (2004) Plasminogen activator inhibitor-1 in the pathogenesis of asthma. Exp. Biol. Med., 229, 138-146.

3. Churg, A., Wang, R.D., Tai, H., Wang, X., Xie, C. & Wright, J.L. (2004) Tumor necrosis factor-alpha drives 70% of cigarette smoke-induced emphysema in the mouse. Am. J. Respir. Crit. Care Med., 170, 492-498.

4. Dunnill, M.S. (1962) Quantitative methods in the study of pulmonary pathology. Thorax, 17, 8.

5. Gauldie, J., Kolb, M., Ask, K., Martin, G., Bonniaud, P. & Warburton, D. (2006) Smad3 signaling involved in pulmonary fibrosis and emphysema. Proc. Am. Thorac. Soc., 3, 696-702.

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