Preparation of Optically Active β-Amino Acids from Microbial Polyester Polyhydroxyalkanoates-Reference-Cited by-同舟云学术

Preparation of Optically Active β-Amino Acids from Microbial Polyester Polyhydroxyalkanoates

Published:2001-11 Issue:11 Volume:2001 Page:498-499
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Park Sang Hyun¹²,Lee Seung Hwan¹²,Lee Sang Yup¹

Affiliation:

1. Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical Engineering and BioProcess Engineering Research Center, Korea Advanced Institute of Science and Technology, 373-1 Kusong-dong, Yusong-gu, Taejon 305-701, Korea

2. ChiroBio Inc., #2324 Undergraduate Building 2, 373-1 Kusong-dong, Yusong-gu, Taejon 305-301, Korea

Abstract

An efficient method for the preparation of optically active ethyl β-aminobutyrate from the biopolymer, poly-( R)-(-)-3-hydroxybutyrate (PHB) obtained from bacterial cells has been established using chemical transformations: simple recovery of PHB from bacterial cells followed by acidic alcoholysis, tosylation, nucleophilic substitution by azide, and an indium mediated reduction.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823401103168640

Reference14 articles.

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