Affiliation:
1. Department of Chemistry, Faculty of Science, Ain Shams University, 11566 Abbasia, Cairo, Egypt
Abstract
3-(2-Thienyl)acryloyl isothiocyanate reacts additively with hydrazine hydrate, phenylhydrazine, 2-pyridyl hydrazine, (thio) semicarbazides, as well as benzoyl- and ethoxycarbonyl hydrazine. Simultaneous or subsequent cyclisation of the resulting 1:1 adducts in acidic or alkaline media yields substituted 1,3,4-thiadiazoles or 1,2,4-triazoles respectively.
Cited by
7 articles.
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2. Nano nickel [1,2,4]‐triazole‐3‐thiones complex: Design, sonochemical synthesis, and antimicrobial evaluation;Journal of Heterocyclic Chemistry;2020-07-28
3. Utility of 3-(thiophen-2-yl)prop-2-enoyl isothiocyanate in heterocyclic synthesis;Journal of Chemical Research;2019-07-11
4. Synthesis of Some New Heterocycles Derived from Novel 2-(1,3-Dioxisoindolin-2-yl)Benzoyl Isothiocyanate;Journal of Heterocyclic Chemistry;2015-04-22
5. Synthesis and Antimicrobial Evaluation of Thieno[2,3-d]-pyrimidine, Thieno[2′,3′:4,5]pyrimido[1,2-a][1,3,5]triazine, Thieno[2,3-d]-1,3-thiazine and 1,2,4-Triazole Systems;Chemical and Pharmaceutical Bulletin;2015