Studies with 2H pyranones: Synthesis of new 3-substituted-4-hydroxy-2H-pyran-2-ones

Author:

Al-Saleh Balkis1,Al-Awadi Nouria1,Al-kandari Halema1,Abdel-Khalik Mervat Mohammed1,Elnagdi Mohamed Hilmy12

Affiliation:

1. Department of Chemistry, Faculty of Science, University of Kuwait, PO Box 5969, Safat, 13060 Kuwait

2. Department of Chemistry, Faculty of Science, Cairo University, Giza, A.R. Egypt

Abstract

3-Acetyl-4-hydroxy-6-methyl-2H-pyran-2-one 1a condensed with N,N-dimethylformamide dimethyl acetal yielding the enaminone 3a. The latter reacted with a variety of reagents affording pyridine derivatives 11, benzofuranoylpyranes 14 and 17, pyranylpyranes 22, pyranylpyrazole 29a,b and pyranylisoxazole 33.

Publisher

SAGE Publications

Subject

General Chemistry

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