Affiliation:
1. Department of Chemistry, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, P. R. China
Abstract
A synthesis of 4-aryl-7,7-dimethyl-5-oxo-3,4,5,6,7,8-hexahydrocoumarin from aromatic aldehyde, 5,5-dimethyl-1, 3-cyclohexadion and Meldrum's acid catalysed by hexadecyltrimethylammonium bromide in water is described. This method provides several advantages such as mild reaction conditions, simple work-up procedure and environment friendly.
Cited by
4 articles.
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1. One-pot synthesis of 4-aryl-7,7-dimethyl-5-oxo-3,4,5,6,7,8-hexahydrocoumarin derivatives in glycerol;Green Chemistry Letters and Reviews;2017-05-18
2. Enantioselective synthesis of enol lactones from tandem Michael addition/lactonization catalyzed by a chiral squaramide catalyst;Tetrahedron: Asymmetry;2014-02
3. Chapter 1 Dimedone: A Versatile Precursor for Annulated Heterocycles;Advances in Heterocyclic Chemistry Volume 98;2009
4. A Clean Method for Producing 4-Aryl-7,7-dimethyl-5-oxo-3,4,5,7,8-hexahydrocoumarin in Aqueous Media;ChemInform;2006-01-17