Use of 5-methoxy, 6-methoxy and 7-methoxy-α-tetralones in the Synthesis of Diterpenes, Sesquiterpenes and Other Natural Products-Reference-Cited by-同舟云学术

Use of 5-methoxy, 6-methoxy and 7-methoxy-α-tetralones in the Synthesis of Diterpenes, Sesquiterpenes and Other Natural Products

Published:2008-04 Issue:4 Volume:2008 Page:181-187
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Poon Po S.¹,Banerjee Ajoy K.¹,Vera William J.¹,Mora Henry D.¹,Laya Manuel S.¹,Bedoya Liadis¹,Cabrera Elvia V.²,Melean Carlos E.²

Affiliation:

1. Instituto Venezolano de Investigaciones Científicas (IVIC), Centro de Química, Apartado-21827, Caracas-1020A, Venezuela

2. Departamento de Química, Facultad Experimental de Ciencias, Universidad del Zulia, Maracaibo, Venezuela

Abstract

The transformations of 5-methoxy, 6-methoxy and 7-methoxy-α-tetralones are described. Studies on the synthesis of diterpenes veadeiroic acid 12, triptolide 18, sesquiterpenes biflorin 25, mansonone F 26, cacalol 39 and a potential intermediate for 11-deoxydaunomycinone 59 from 5-methoxy-α-tetralone 1 are discussed. Several intermediates for diterpenoid compounds and a total synthesis of phytoalexin orchinol 53 from 6-methoxy-α-tetralone 2 have been accomplished. 7-Methoxy-α-tetralone 3 has proved to be a suitable starting material for a simple and short synthesis of cadinene dihydrochloride 45.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823408784549915

Reference69 articles.

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