Synthesis of Enynones from Alkynes, Alkynyl Ketones and Aromatic Aldehydes Using the TiCl4/Et3N Reagent System-Reference-Cited by-同舟云学术

Synthesis of Enynones from Alkynes, Alkynyl Ketones and Aromatic Aldehydes Using the TiCl4/Et3N Reagent System

Published:2006-09 Issue:9 Volume:2006 Page:566-568
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Periasamy Mariappan¹,Karunakar Galla V.¹,Bharathi Pandi¹

Affiliation:

1. School of Chemistry, University of Hyderabad, Central University PO, Hyderabad-500 046, India

Abstract

Alkynyltitanium species, prepared in situ from alk-1-ynes using the TiCl4/Et3N reagent system, react with aromatic aldehydes to give enynones 2 in 49–38% yields. Reaction of alkynyl aryl ketones with aromatic aldehydes and the TiCl4/Et3N reagent gives the enynones 2 in 78–92% yields.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823406778521446

Reference10 articles.

1. A simple method for the conversion of propargyl alcohols to symmetrical 1,5-diynes using low valent titanium reagents

2. Direct Metalation of 1-Alkynes Using TiCl4/Et3N and the Reactions of the Organotitanium Intermediates with Electrophiles

3. Organotitanium Reagents in Organic Synthesis

4. Straightforward Synthesis of Panaxytriol: An Active Component of Red Ginseng

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Palladium(II) on 4 Å Molecular Sieves: A Simple and Reusable Catalyst for the Preparation of Ynones;Catalysis Letters;2020-05-09

2. Copper-Catalyzed Cascade Aminoalkynylation–Oxidation of Propargylic Alcohols: Stereospecific Synthesis of (Z)-2-Amino Conjugated Enynals/Enynones;Organic Letters;2018-08-29

3. Alternative formation of amides and β-enaminones from aroyl chlorides using the TiCl4-trialkylamine reagent system;Organic & Biomolecular Chemistry;2018

4. Synthesis of Enynones from Alkynes, Alkynyl Ketones and Aromatic Aldehydes Using the TiCl4/Et3N Reagent System.;ChemInform;2007-01-16