Hypervalent Iodine in Synthesis 91: A Mild and Efficient Method for the Halogenation of 6-Methyluracil Derivatives-Reference-Cited by-同舟云学术

Hypervalent Iodine in Synthesis 91: A Mild and Efficient Method for the Halogenation of 6-Methyluracil Derivatives

Published:2002-12 Issue:12 Volume:2002 Page:624-625
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Cheng Dong Ping¹,Chen Zhen Chu¹,Zheng Qin Guo²

Affiliation:

1. Department of Chemistry, Zhejiang University, Xixi Campus, Hangzhou, 310028, P.R. China

2. Pharmaceutical Sciences, School of Life & Health Sciences, Aston University, Birmingham B4 7ET, UK

Abstract

The combined reagent of iodobenzene diacetate (or polymer-supported iodobenzene diacetate) with iodine or bromine was used as an effective halogenative agent of 6-methyluracil derivatives to the corresponding 5-halo-6-methyluracil derivatives at room temperature with high yields.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823402103171032

Reference20 articles.

1. Nucleic acid related compounds. 38. Smooth and high-yield iodination and chlorination at C-5 of uracil bases and p-toluyl-protected nucleosides

2. Synthesis of 5,6-bis(alkyn-1-yl)pyrimidines and related nucleosides

3. Fluoride-Assisted Nucleophilic Substitution of 6-Alkyl-5-bromouracils with Nitrogen-Containing Heterocycles

4. Nucleoside und verwandte Verbindungen. VII. Alkylierung und Glykosidierung der Silyl-derivate 6-substituierter Uracile

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