Preparation, X-ray Structure and Propylaminolysis of 7,7-dichloro-5,7-dihydro-thieno[3,4-b]pyridin-5-one-Reference-Cited by-同舟云学术

Preparation, X-ray Structure and Propylaminolysis of 7,7-dichloro-5,7-dihydro-thieno[3,4-b]pyridin-5-one

Published:2007-06 Issue:6 Volume:2007 Page:373-376
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

van Es Theodorus¹,Staskun Benjamin²³,Fernandes Manuel A.²

Affiliation:

1. Department of Biochemistry and Microbiology, Cook College, Rutgers, The State University of New Jersey, 08903-0231, USA

2. School of Chemistry, University of the Witwatersrand, P.O.Wits, 2050, South Africa

3. Honorary Associate, Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW 2109, Australia

Abstract

Refluxing 2-methylpyridine-3-carboxylic acid with thionyl chloride for 6–7 h gave (∼50%) title compound dichlorothienolactone 2 as was confirmed by a X-ray structure analysis. The propylaminolysis of 2 provides a new and convenient access to highly functionalised pyrrolo[3,4- b]pyridine derivatives.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823407X225392

Reference14 articles.

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4. VörbruggenH., Advances in Heterocyclic Chemistry, Ed. KatritzkyA.R., 1990, 9, 129. Academic Press, San Diego.

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