Substituted Pyridopyrimidinones: Oxidation of 2-Hydroxypyrido [1,2-a]Pyrimidin-4(H)-One-Reference-Cited by-同舟云学术

Substituted Pyridopyrimidinones: Oxidation of 2-Hydroxypyrido [1,2-a]Pyrimidin-4(H)-One

Published:2009-02 Issue:2 Volume:2009 Page:93-94
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Abass Mohamed¹,Mayas Aisha S.¹

Affiliation:

1. Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo 11757, Egypt

Abstract

A simple method for the oxidation of 2-hydroxypyrido[1,2-a]pyrimidin-4( H)-one is described. Treatment of the title compound with selenium dioxide in dioxane/water, followed by warming leads directly to 1 H-pyrrolo[2,3- b]pyridine-2,3-dione. The method is shown to be effective for preparation of the last compound which is used as a synthon for some antihypertensive agents.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823409X402519

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4. 300. Tautomeric azines. Part II. The structure of “malonyl-α-aminopyridine” and its alkylation products: mesomeric betaines with six-membered rings

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