The Synthesis of Benzhydroximoyl Chloride and Nitrile Oxides under Solvent Free Conditions-Reference-Cited by-同舟云学术

The Synthesis of Benzhydroximoyl Chloride and Nitrile Oxides under Solvent Free Conditions

Published:2007-01 Issue:1 Volume:2007 Page:26-28
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Bigdeli Mohammad A.¹,Mahdavinia Gholam Hossein¹,Jafari Saeed¹

Affiliation:

1. Faculty of Chemistry, Teacher Training University, 49 Mofateh St., Tehran, Iran

Abstract

Benzhydroximoyl chlorides were prepared as nitrile oxide precursors with acidic (HCl) silica gel/Oxone in solvent less media in excellent yields with the selective chlorination of aldoximes vs. aromatic substitution. Nitrile oxides were generated by Huisgen's method in solvent free conditions and were trapped via reactions with styrene yielding isoxazolines. The one pot preparation of isoxazolines from substituted benzaldehyde oximes was successfully investigated.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823407780199621

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