Mechanism of hydrolysis of substituted N-thiazolylcarbamate esters in OH- solutions-Reference-Cited by-同舟云学术

Mechanism of hydrolysis of substituted N-thiazolylcarbamate esters in OH- solutions

Published:2006-10 Issue:10 Volume:2006 Page:664-667
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Araújo M. Eduarda M.¹,Norberto Fátima¹²,Pamplona Teresa¹,Iley Jim³

Affiliation:

1. CQB and Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal

2. Departamento de Ciências da Saúde, Universidade Lusófona, 1749-024 Lisboa, Portugal

3. Chemistry Department, The Open University, Milton Keynes MK7 6AA, UK

Abstract

Substituted secondary N-thiazolylcarbamate esters and some tertiary N-methyl, N-thiazolyl carbamate esters have been synthesised and the mechanism of the OH- catalysed hydrolyses investigated. These proved to be E1cB and BAc2 respectively, and this behaviour was compared with that of other carbamates.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823406779173578

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