Synthesis of Amino Substituted Pyrazoles

Author:

Singh Okram Mukherjee1,Ahmed Mohammad Farooque1,Singh Sarangthem Joychandra1,Lee Sang-Gyeong2

Affiliation:

1. Department of Chemistry, Manipur University, Canchipur –795003, Manipur, India

2. Department of Chemistry and Research Institute of Life Science, Gyeongsang National University, JinJu, GyeongNam 660-701, South Korea

Abstract

An efficient and convenient synthesis of substituted pyrazoles with aryl and heteroarylamino substituents attached to the C-3 and C-5 positions by the action of hydrazine hydrate on either ketene N,S-acetals or mixed N,N-aminals hydrate is reported.

Publisher

SAGE Publications

Subject

General Chemistry

Reference25 articles.

1. Reviews: (a) ElgueroJ., In Comprehensive Heterocyclic Chemistry II; KatritzkyA.R., and ReesC.W., ScrivenE.F.V., eds, Pergamon Press: Oxford, 1996; Vol. 3, p 1;

2. Vol. 6, p 347, (c) K.Y. Lee, J.M. Kim and J.N. Kim, Tetrahedron Lett. 2003, 44, 6737 and references therein.

3. (a) ElgueroJ., In Comprehensive Heterocyclic Chemistry II; KatritzkyA.R., and ReesC.W., ScrivenE.F.V., eds, Pergamon Press: Oxford, 1996; Vol. 3, p 1;

4. (b) A.N. Kost and I.I. Grandberg, In Advances in Heterocyclic Chemistry, A.R. Katritzky and A. J. Boulton, eds, Academic Press: New York, 1966; Vol. 6, p 347,

5. (c) K.Y. Lee, J.M. Kim and J.N. Kim, Tetrahedron Lett. 2003, 44, 6737 and references therein.

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