Terpenes from Eunicea Laciniata and Plexaurella Nutans

Author:

Bashyal Bharat1,Desai Prashant1,Rao Karumanchi V.2,Hamann Mark T.2,Avery Bonnie A.3,Reed John K.4,Avery Mitchell A.1

Affiliation:

1. Department of Medicinal Chemistry, University of Mississippi, MS 38677, USA

2. Department of Pharmacognosy and National Center for Natural Product Research, University of Mississippi, MS 38677, USA

3. Department pf Pharmaceutics, School of Pharmacy, University of Mississippi, MS 38677, USA

4. Harbor Branch Oceanographic Institution, Fort Pierce, Florida, USA

Abstract

A new 7,8–epoxydolabella–3(E)–12(18)–diene (1), diterpenoid together with three known compounds were isolated from a Honduras gorgonian Eunicea laciniata. The relative stereochemistry of 1 was established by spectroscopic studies and the antiprotozoal and antimicrobial activities of dolabellane diterpenoids 2–4 are reported. Three known cadinane type sesquiterpenes were also isolated from Honduras gorgonian Plexaurella nutans.

Publisher

SAGE Publications

Subject

General Chemistry

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