Conversion of 3-Arylphthalides into Anthrones with a Methylcarbonyl Substituent at the C-10 Position-Reference-Cited by-同舟云学术

Conversion of 3-Arylphthalides into Anthrones with a Methylcarbonyl Substituent at the C-10 Position

Published:2009-03 Issue:3 Volume:2009 Page:151-153
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Bieniek Adam¹,Bartczak Monika M.¹,Epsztajn Jan¹

Affiliation:

1. Department of Organic Chemistry, Faculty of Chemistry, University of Łódź, 90-136 Łódź, Narutowicza 68, Poland

Abstract

The ortho-lithiation of a benzoic acid anilide followed by condensation with an aryl aldehyde gave a 3-arylphthalide. Reductive alkylation with 1-methoxy-1-trimethylsilyloxyethene gave a substituted aromatic carboxylic acid which was cyclised to an anthrone bearing a methoxycarbonyl methylene unit at C-10.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823409X416956

Reference12 articles.

1. 10-Phenylbutyryl-substituted anthracenones as inhibitors of keratinocyte growth and LTB4 biosynthesis

2. 2-Arylalkyl-substituted anthracenones as inhibitors of 12-lipoxygenase enzymes. 1. Structure–activity relationships of the terminal aryl ring

3. 2-Arylalkyl-substituted anthracenones as inhibitors of 12-lipoxygenase enzymes. 2. Structure–activity relationships of the linker chain

4. Three anthrones from Rubus ulmifolius

5. Total Synthesis and Structure Assignment of the Anthrone C-Glycoside Cassialoin

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. ChemInform Abstract: Conversion of 3-Arylphthalides into Anthrones with a Methylcarbonyl Substituent at the C-10 Position.;ChemInform;2009-08-18