Cu(OAc)2/Malononitrile/Water: A Simple Reaction System for Synthesis of Aromatic Nitriles from Aldoximes-Reference-Cited by-同舟云学术

Cu(OAc)2/Malononitrile/Water: A Simple Reaction System for Synthesis of Aromatic Nitriles from Aldoximes

Published:2018-12 Issue:12 Volume:42 Page:595-597
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Ma Xiaoyun¹,He Daqin¹,Chen Zhengjian¹

Affiliation:

1. School of Chemistry and Materials Science, Guizhou Education University, Guiyang 550018, P.R. China

Abstract

A simple method for the preparation of nitriles in moderate to good yield has been achieved by treatment of aromatic and heterocyclic aldoximes with malononitrile in water at reflux in the presence of copper acetate as catalyst. Arylaldoximes with an electron-donating group showed the highest reactivity, their conversion being achievable at room temperature.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751918X15411700157951

Reference22 articles.

1. Reaction of triflyl-imidazole with aldoximes: facile synthesis of nitriles and formation of novel aldoxime-bis(N-triflyl)-imidazole adducts

2. SOCl2/β-Cyclodextrin: A New and Efficient Catalytic System for Beckmann Rearrangement and Dehydration of Aldoximes Under Aqueous Condition

3. Highly efficient Beckmann rearrangement and dehydration of oximes

4. Polyethylene glycol supported phosphorus chloride: An efficient and recyclable catalyst for the preparation of nitriles from aldoximes

5. Copper immobilized on aminated ferrite nanoparticles by 2-aminoethyl dihydrogen phosphate (Fe3O4@AEPH2-CuII) catalyses the conversion of aldoximes to nitriles

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