One-Pot Tandem Approach for the Synthesis of Quinazolinones from ortho-Aminobenzamides, Benzyl Halides and Benzyl Alcohols-Reference-Cited by-同舟云学术

One-Pot Tandem Approach for the Synthesis of Quinazolinones from ortho-Aminobenzamides, Benzyl Halides and Benzyl Alcohols

Published:2012-12 Issue:12 Volume:36 Page:701-702
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Motevalli Kourosh¹,Mirzazadeh Roghieh²,Yaghoubi Zahra³

Affiliation:

1. Department of Applied Chemistry, Faculty of Science, Islamic Azad University, South Tehran Branch, Tehran, Iran

2. Department of Biochemistry, Pasteur Institute of Iran, Tehran, Iran

3. Industrial Faculty, Islamic Azad University, South Tehran Branch, 4 Islamic Azad University, Tehran, Iran

Abstract

A one-pot tandem procedure is described for the synthesis of quinazolinones from benzyl halides or benzyl alcohols and ortho-aminobenzamides leading to the production of quinazolinones with high yields under mild conditions in DMSO without requiring an additional oxidant. According to the current method benzyl chlorides, benzyl bromides and benzyl alcohols bearing a range of substituents are suitable substrates.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751912X13505766800606

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