Affiliation:
1. Department of Chemistry, Zahedan Branch, Islamic Azad University, Zahedan, Iran
Abstract
A novel method for oxazine ring formation has been established using the reaction of kojic acid and aromatic aldehydes with methyl carbamate in the presence of p-toluenesulfonic acid in aqueous media to afford 4-aryl-6-hydroxymethyl-1,4-dihydropyrano[3,2-e][1,3] oxazine-2,8-diones in excellent yields. The present method does not involve any hazardous organic solvent. Therefore, this procedure could be classified as green chemistry.
Cited by
1 articles.
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