Synthesis and Antioxidant Properties of Novel Pyrimidine-Containing Heterocycles-Reference-Cited by-同舟云学术

Synthesis and Antioxidant Properties of Novel Pyrimidine-Containing Heterocycles

Published:2016-05 Issue:5 Volume:40 Page:299-304
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Salem Marwa Sayed¹,Errayes Asma Omer²

Affiliation:

1. Synthetic Organic Chemistry Laboratory, Chemistry Department, Faculty of Science, Ain Shams University, Abbasiya, Cairo 11566, Egypt

2. Chemistry Department, Faculty of Science, Tripoli University, PO Box 13494, Tripoli, Libya

Abstract

4-(Benzo[ d][1,3]dioxol-5-yl)-2-hydrazinyl-6-oxo-1,6-dihydropyrimidine-5-carbonitrile was utilised to construct fused heterocyclic systems, namely triazolopyrimidines, as well as non-fused heterocyclic systems such as pyrazole and dioxopyrazolidine derivatives. The antioxidant activity of the new compounds was evaluated. Most of the synthesised compounds have potent antioxidant activity.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751916X14605482579576

Reference36 articles.

1. One-pot Synthesis of 1,2,3,4-Tetrahydropyrimidin-2(1H)-thione Derivatives and their Biological Activity

2. 2-Cyanoaminopyrimidines as a class of antitumor agents that promote tubulin polymerization

3. Utility of 6-amino-2-thiouracil as a precursor for the synthesis of bioactive pyrimidine derivatives

4. Synthesis and in vitro cytotoxicity studies of novel triazolo[4,3-b]pyridazinones

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