An Unexpected Catalytic Synthesis of Novel and Known Bis(Pyrazolyl) Methanes by the use of α-aryl-N-phenyl Nitrones in Aqueous Media-Reference-Cited by-同舟云学术

An Unexpected Catalytic Synthesis of Novel and Known Bis(Pyrazolyl) Methanes by the use of α-aryl-N-phenyl Nitrones in Aqueous Media

Published:2014-10 Issue:10 Volume:38 Page:600-603
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Eskandari Khalil¹,Karami Bahador¹,Khodabakhshi Saeed²

Affiliation:

1. Department of Chemistry, Yasouj University, P.O. Box 353, Yasouj, 75918-74831, Iran

2. Nanotechnology Research Center, Research Institute of Petroleum Industry, Tehran, Iran

Abstract

Reaction of-aryl- N-phenyl nitrones with 3-methyl-1-phenyl-2-pyrazoline-5-one in the presence of a catalytic amount of silica tungstic acid in EtOH/H2O afforded, unexpectedly, high yields of bis(3-hydroxy-1-phenylpyrazolyl)-arylmethanes instead of the two possible 1,3-addition products. This is the first report of the synthesis of bis(3-hydroxy-1-phenylpyrazolyl)-arylmethanes via the reaction of nitrones and a pyrazolin-5-one. A possible mechanism for the process is suggested.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751914X14114871789226

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