The Trifluoromethylation of Iminium Salts by the Addition of Trifluoromethyltrimethylsilane-Reference-Cited by-同舟云学术

The Trifluoromethylation of Iminium Salts by the Addition of Trifluoromethyltrimethylsilane

Published:2016-06 Issue:6 Volume:40 Page:379-381
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Liu Haidong¹²,Chen Bo¹,Cai Jin³,Chen Junqing³,Ji Min¹²

Affiliation:

1. School of Biological Science and Medical Engineering, Southeast University, Si Pai Lou 2#, Nanjing City 210096, P.R. China

2. Suzhou Key Laboratory of Biomaterials and Technologies & Collaborative Innovation Center of Suzhou Nano Science and Technology, Suzhou, 215123, P.R. China

3. School of Chemistry and Chemical Engineering, Southeast University Si Pai Lou 2#, Nanjing City 210096, P.R. China

Abstract

Eleven trifluoromethylated amines were synthesised in high yield (up to 98%) under metal-free and oxidant-free conditions using iminium salts as starting material and the addition of trifluoromethyltrimethylsilane in dimethylformide containing potassium fluoride.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751916X14636698285461

Reference24 articles.

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4. The Many Roles for Fluorine in Medicinal Chemistry

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