Affiliation:
1. Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, 91775-1436 Mashhad, Iran.
Abstract
The condensation reaction of 6-acetyl-3-amino-5-aryl-2-phenyl-2,5-dihydropyridazine-4-carbonitrile with triethyl orthoformate and then with hydrazine hydrate to obtain the new fused bicyclic 4-aryl-5-hydrazinyl-3-(1-hydrazonoethyl)-1-phenyl-1,4-dihydropyrimido[4,5-c]pyridazines via the Dimroth rearrangement is reported. Further cyclisation was achieved by the treatment of latter compounds with triethyl orthoformate to afford several derivatives of a novel tetracyclic fused system [1,2,4] triazolo[4″,3″:1′,6′]pyrimido[4′,5′:3,4]pyridazino[1,6-d][1,2,4]triazine.
Cited by
6 articles.
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1. Bicyclic 6-6 Systems With One Bridgehead (Ring Junction) Nitrogen Atom: Three Extra Heteroatoms (2:1);Comprehensive Heterocyclic Chemistry IV;2022
2. Bicyclic 6-6 Systems: Other Four Heteroatoms 2:2;Comprehensive Heterocyclic Chemistry IV;2022
3. 1,2,4-Triazines and Their Benzo Derivatives;Comprehensive Heterocyclic Chemistry IV;2022
4. Synthesis and Density Functional Theory Study of [1,2,3]Triazolo[4,5-d][1,2,4] Triazolo[4,3-a]Pyrimidine Derivatives: A Novel Heterocyclic System;Journal of Chemical Research;2016-10
5. Synthesis of Some Derivatives of Pyrimido[5,4-e]Tetrazolo[5,1-c][1,2,4]triazine; a Novel Heterocyclic System;Journal of Chemical Research;2015-10