Facile synthesis of bis-thiosemicarbazone derivatives as key precursors for the preparation of functionalised bis-thiazoles-Reference-Cited by-同舟云学术

Facile synthesis of bis-thiosemicarbazone derivatives as key precursors for the preparation of functionalised bis-thiazoles

Published:2016-07 Issue:7 Volume:40 Page:385-392
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Arafa Wael A.A.¹²,Badry Mohamed G.²

Affiliation:

1. Chemistry Department, College of Science, Aljouf University, P.O. Box 2014, Sakaka, Aljouf, Kingdom of Saudi Arabia

2. Chemistry Department, Faculty of Science, Fayoum University, 63514, Fayoum, Egypt

Abstract

A new class of bis-thiosemicarbazones was designed and synthesised by the condensation of 2,6-diformylphenol derivatives and thiosemicarbazide using either ultrasound or conventional methods. Both thiosemicarbazone groups of these derivatives underwent a heterocyclisation process to give a series of novel bis-thiazole derivatives as major products. The structures of all the synthesised compounds were characterised by multinuclear NMR (1H and 13C), IR, HRMS and elemental analyses.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751916X14639296902648

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