An Efficient Synthesis of 2,4-Dichloro-3,5-Difluorobenzoic Acid-Reference-Cited by-同舟云学术

An Efficient Synthesis of 2,4-Dichloro-3,5-Difluorobenzoic Acid

Published:2015-07 Issue:7 Volume:39 Page:414-415
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Zhou Weiyou¹²,Feng Xiaohu¹³,Yu Shuitao¹³,Xia Zhengjun¹³,Chen Yang¹³,Chen Zaixin¹³

Affiliation:

1. Yabang Medical Research Institute, Changzhou 213145, P.R. China

2. Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou 213164, P.R. China

3. Jiangsu Novel Quinolone Antibacterial Drugs Engineering Research Center, Changzhou 213145, P.R. China

Abstract

2,4-Dichloro-3,5-difluorobenzoic acid was synthesised from the commercially available 4-chloro-3,5-difluorobenzonitrile in good yield by a reaction sequence involving nitration, selective reduction, diazotisation and chlorination.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751915X14358518790739

Reference16 articles.

1. Synthesis and antitumor activity studies of some new fused 1,2,4-triazole derivatives carrying 2,4-dichloro-5-fluorophenyl moiety

2. Transformations of Chloroarenes, Catalyzed by Transition-Metal Complexes

3. Indirect Formation of Carboxylic Acids via Anhydrides in the Palladium-Catalyzed Hydroxycarbonylation of Aromatic Halides

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. An Efficient Synthesis of 3,5-Dimethoxy-2,4-Difluorobenzoic Acid;Journal of Chemical Research;2017-04