A Facile and Diastereoselective access to Functionalised Benzopyrano[3,4-a] Quinolizines via a Pyridine-Based Three-Component Reaction-Reference-Cited by-同舟云学术

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A Facile and Diastereoselective access to Functionalised Benzopyrano[3,4-a] Quinolizines via a Pyridine-Based Three-Component Reaction

Published:2017-12 Issue:12 Volume:41 Page:688-692
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Esmaeili Abbas Ali¹,Moradi Abbas²,Zangouei Mahdieh¹,Fakhari Ali Reza³,Tabibi Tooba¹

Affiliation:

1. Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Iran

2. Chemistry Department, University of Birjand, Birjand, Iran

3. Department of Chemistry, Faculty of Science, Shahid Beheshti University, G.C., PO Box 19396-4716, Evin, Tehran, I.R. of Iran

Abstract

The reaction of 2-oxo-2 H-chromene-3-carbonitriles with dialkyl acetylenedicarboxylates and pyridines results in a three-component condensation reaction in which the 2-oxo-2 H-chromene-3-carbonitrile group acts as a dipolarophile to produce benzopyrano[3,4- a] quinolizines under mild conditions in good yield.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751917X15105690662872

Reference23 articles.

1. Antimalarial activity and structure-activity relationships of protoberberine alkaloids

2. Quinolizidine alkaloids from the curare adjuvant Clathrotropis glaucophylla

3. One step synthesis of pyrimido[1,2-a][1,8]naphthyridinones, pyrido[1,2-a]pyrimidinones and 1,8-naphthyridinones. Antihypertensive agents. V

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