Synthesis of Dialkyl {(aryl)[2,2-Dimethyl-4-oxo-6-(Piperidin-1-yl)-4H-[1,3]Dioxin-5-yl]Methyl}Phosphonate by Reaction of Meldrum's Acid, Aryl Aldehydes and Trialkyl Phosphites in the Presence of Piperidine-Reference-Cited by-同舟云学术

Synthesis of Dialkyl {(aryl)[2,2-Dimethyl-4-oxo-6-(Piperidin-1-yl)-4H-[1,3]Dioxin-5-yl]Methyl}Phosphonate by Reaction of Meldrum's Acid, Aryl Aldehydes and Trialkyl Phosphites in the Presence of Piperidine

Published:2013-07 Issue:7 Volume:37 Page:402-403
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Khosravi Reza¹,Hosseini-Tabatabaei Mohammad R.²,Forghaniha Ali¹

Affiliation:

1. Department of Chemistry, Arak Branch, Islamic Azad University, Arak, Iran

2. Department of Chemistry, Islamic Azad University, Zahedan Branch, PO Box 98135-978, Zahedan, Iran

Abstract

A four-component reaction between Meldrum's acid, aryl aldehydes with trialkyl phosphites in the presence of piper-idine has been developed. The reaction affords dialkyl {(aryl)[2,2-dimethyl-4-oxo-6-(piperidin-1-yl)-4 H-[1,3]dioxin-5-yl]methyl}phosphonate in moderate to good yields in a one-pot process.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751913X13701025495780

Reference19 articles.

1. Ion pairing and reactivity of enolate anions. 7. A spectacular example of the importance of rotational barriers: the ionization of Meldrum's acid

2. LIV.—A β-lactonic acid from acetone and malonic acid

3. The Structure of Meldrum's Supposed β-Lactonic Acid

4. Meldrum's acid

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. ChemInform Abstract: Synthesis of Dialkyl {(Aryl)[2,2-dimethyl-4-oxo-6-(piperidin-1-yl)-4H- [1,3]dioxin-5-yl]methyl}phosphonate by Reaction of Meldrum′s Acid, Aryl Aldehydes and Trialkyl Phosphites in the Presence of Piperidine.;ChemInform;2013-12-19