A Facile Synthesis of Novel Spiro Indoline-Based Heterocycles through 1,3-Dipolar Cycloaddition Reactions-Reference-Cited by-同舟云学术

A Facile Synthesis of Novel Spiro Indoline-Based Heterocycles through 1,3-Dipolar Cycloaddition Reactions

Published:2012-02 Issue:2 Volume:36 Page:94-95
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Souzangarzadeh Saeid¹,Bazian Atiye¹,Anaraki-Ardakani Hossein²

Affiliation:

1. Department of Chemistry, Shahre-Rey Branch, Islamic Azad University, Tehran, Iran

2. Department of Chemistry, Mahshahr Branch, Islamic Azad University, Mahshahr, Iran

Abstract

A simple and efficient one-pot route for the synthesis of novel spiro [indolin–3,3'-1,2,4-triazol] derivatives by 1,3-dipolar cycloaddition reaction of nitrilimines and isatin imines under classical or microwave irradiation conditions is described. Spiro heterocyclic compounds possess pharmacological properties such as antimicrobial, analgesic, anti-inflammatory, antimycobacterial, antifungal, antitumor and antiviral activities.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751912X13279492179667

Reference21 articles.

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2. Synthesis, biological evaluation and molecular docking of novel series of spiro [(2H,3H) quinazoline-2,1′- cyclohexan]-4(1H)- one derivatives as anti-inflammatory and analgesic agents

3. An atom economic synthesis and antitubercular evaluation of novel spiro-cyclohexanones

4. Efficient microwave enhanced regioselective synthesis of a series of benzimidazolyl/triazolyl spiro [indole-thiazolidinones] as potent antifungal agents and crystal structure of spiro[3H-indole-3,2′-thiazolidine]-3′(1,2,4-triazol-3-yl)-2,4′(1H)-dione

5. Discorhabdin W, the First Dimeric Discorhabdin

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