One-Pot Sequence Synthesis of Azetidin-2-One Using Diethyl Chlorophosphate-Reference-Cited by-同舟云学术

One-Pot Sequence Synthesis of Azetidin-2-One Using Diethyl Chlorophosphate

Published:2012-02 Issue:2 Volume:36 Page:118-120
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Zarei Maaroof¹

Affiliation:

1. Department of Chemistry, College of Sciences, Hormozgan University, Bandar Abbas 71961, Iran

Abstract

A simple and convenient synthesis of 2-azetidinone derivatives from the reaction of a pre-mixture of amines and aldehydes with carboxylic acids in the presence of diethyl chlorophosphate by [2+2] cycloaddition reaction is described. Separation and purification of imines as intermediates were not required. The methodology is convenient and good to excellent yields of products were obtained with simple purification.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751912X13282660033937

Reference40 articles.

1. N-Thiolated β-Lactams

2. Biological Activity of Some Monocyclic- and Bicyclic β-Lactams with Specified Functional Groups

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