Affiliation:
1. College of Chemical Engineering, Nanjing Tech University, Nanjing, Jiangsu 210009, PR China
Abstract
A facile strategy for enantioselective synthesis of ( R)-salmeterol is described via a chiral auxiliary starting from 2-bromo-1-(2,2-dimethyl-4 H-1,3-benzodioxin-6-yl)ethanone through four or five steps. The product was obtained in good purity, enantiomeric excess and yield.
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