Facile and Efficient One-Pot Synthesis of Highly Functionalised 1,2,3,5-Tetrahydroimidazo[1,2-A]Pyrimidines-Reference-Cited by-同舟云学术

Facile and Efficient One-Pot Synthesis of Highly Functionalised 1,2,3,5-Tetrahydroimidazo[1,2-A]Pyrimidines

Published:2015-04 Issue:4 Volume:39 Page:203-205
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Vojdani Zeinab¹,Mohebat Razieh¹

Affiliation:

1. Department of Chemistry, Islamic Azad University, Yazd Branch, PO Box 89195-155, Yazd, Iran

Abstract

The one-pot, three-component reaction between isocyanides, electron-deficient acetylenic esters and 2-amino-1-methyl-1H-imidazol-4(5H)-one efficiently leads to highly functionalised 1,2,3,5-tetrahydroimidazo[1,2-a]pyrimidines without any activation in excellent yields at room temperature.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751915X14267781816171

Reference15 articles.

1. 2-(Oxadiazolyl)- and 2-(thiazolyl)imidazo[1,2-a]pyrimidines as agonists and inverse agonists at benzodiazepine receptors

2. Synthesis of Acyclo-C-nucleosides in the Imidazo[1,2-a]pyridine and Pyrimidine Series as Antiviral Agents

3. Antifungal activity in vitro of some imidazo[1,2-a]pyrimidine derivatives

4. Synthesis of (aryloxy)alkylamines. 2. Novel imidazo-fused heterocycles with calcium channel blocking and local anesthetic activity

5. Dialkyl bicyclic heterocycles with a bridgehead nitrogen as purine analogs possessing significant cardiac inotropic activity

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Reaction between Benzoic Acid N′-(2-Oxo-2-Phenyl-Ethyl)Hydrazide and Acetylenic Esters in the Presence of Alkyl Isocyanides: One-Pot Synthesis of Highly Functionalized 2,3-Dihydro-1H-Pyrazoles;Polycyclic Aromatic Compounds;2021-10-16

2. Synthesis of highly functionalised 5-membered ring fused pyrimidine derivatives using an isocyanide-based one-pot, three component reaction;Tetrahedron Letters;2020-04

3. The status of isocyanide-based multi-component reactions in Iran (2010–2018);Molecular Diversity;2020-02-18

4. Caffeine catalyzed green synthesis of novel benzo[ a ][1,3]oxazino[6,5- c ]phenazines via a one-pot multi-component sequential protocol in a basic ionic liquid;Chinese Chemical Letters;2017-06

5. Efficient Synthesis of Novel Polyfunctionalized Pyrazole Derivatives via Isocyanide-Based Three-Component Reaction;Polycyclic Aromatic Compounds;2016-12-02