Catalyst-Free Amination of 2-Chloronicotinic Acid in Water under Microwave Irradiation-Reference-Cited by-同舟云学术

Catalyst-Free Amination of 2-Chloronicotinic Acid in Water under Microwave Irradiation

Published:2011-12 Issue:12 Volume:35 Page:709-711
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Li Zheng-hua¹,Xia Zhi-ning¹,Chen Gang¹

Affiliation:

1. College of Chemistry and Chemical Engineering, Chongqing University, Shazheng Street No.174, Shapingba District, Chongqing, 400030, P. R. China

Abstract

A simple, efficient and environmental friendly method for the synthesis of 2-arylaminonicotinic acids derivatives by reacting 2-chloronicotinic acid with anilines with potassium carbonate as the base and water as the media under microwave irradiation is described. The synthesis of 2-arylaminonicotinic acids is important because they are nonsteroidal anti-inflammatory drugs.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751911X13231642443092

Reference24 articles.

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